Pesquisa sobre: DNA TOPOISOMERASE IV 
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Descritor Inglês:   DNA Topoisomerase IV 
Descritor Espanhol:   Topoisomerasa de ADN IV 
Descritor Português:   DNA Topoisomerase IV 
Sinônimos Inglês:   parC Protein
parE Protein  
Categoria:   D08.811.399.403.741.224
D12.776.097.256
Definição Inglês:   A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication. 
Nota Histórica Inglês:   2002; use DNA TOPOISOMERASE IV (NM) 1991-2001 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   36090 
Identificador Único:   D027101 

Ocorrência na BVS:
 

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